This simple supplement may halt Alzheimer's Disease
Saturday, 12 September 2015 | Stuart
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Could a simple supplement halt Alzheimer’s disease?
Alzheimer's patients who took resveratol twice-a-day for a year were found to have fewer dementia biomarkers in their blood and scored better on cognitive tests
Researchers used a technique called Transcranial Magnetic Stimulation which uses a magnetic pulse to trigger electrical charges in the brain cells, forcing them to become more active.
A cheap supplement may halt the progression of Alzheimer’s disease after a trial suggested that dementia sufferers stopped deteriorating while taking it.
Resveratrol is a naturally occurring compound which is found in foods like red grapes, raspberries, dark chocolate and red wine.
Although quantities in food are tiny, high-dose supplements are now available over-the-counter in most health food shops for just a few pounds and purer forms are available from pharmacists.
Scientists enrolled 119 people with mild to moderate Alzheimer’s disease in a trial in which they were given 1g of high-grade resveratrol twice a day for 12 months while a control group received a placebo.
Normally, as Alzheimer’s disease progresses the level of a protein called Abeta40 decreases in the blood. But those taking the supplement showed:
Sufferers who were taking the placebo continued to show decreased levels of Abeta40 and did not improve on cognitive tests.
"Resveratrol is a naturally occurring compound in red wine, chocolate and peanuts and other foods,” said Dr Scott Turner, director of the Memory Disorders Program at Georgetown University Medical Centre, in Washington.
"Number one, we found that resveratrol was safe in older people with Alzheimer’s Disease and number two, it looked like it may have had a beneficial effect on biomarkers and disease progression.
"We had four cognitive measurement levels and one of them showed a benefit of resveratrol treatment. This was the activities of daily living scale, which are things like cooking and using the phone.
Reveratrol activates valuable proteinsThe researchers chose resveratrol because it activates proteins called sirtuins - the same proteins switched on by calorie restriction.